Maxora



Composition: Each MUPS (Multiple Unit Pellet System) tablet contains Esomeprazole Magnesium USP enteric-coated pellets equivalent to Esomeprazole 20 mg.

Pharmacology: The Multiple Unit Pellet System (MUPS) tablet is a kind of multiparticulate system that combines the features of both modified-release tablets and capsules in one dosage form.

Indications:

  • Gastro-Esophageal Reflux Disease (GERD)
  • Risk reduction in NSAID-associated gastric ulcer
  • H. pylori eradication (Triple therapy)
  • Zollinger-Ellison syndrome and idiopathic hypersecretion


Dosage and Administration:
Maxora MUPS tablets should be swallowed whole with liquid. The tablets should not be chewed or crushed.
Indication Adult (≥18 years) Children & Adolescents (12-18 years)
Gastro-Esophageal Reflux Disease (GERD)
Erosive esophagitis		 40 mg once daily for 4 weeks 40 mg once daily for 4 weeks
Maintenance of healing of erosive esophagitis 20 mg once daily 20 mg once daily
Risk reduction in NSAID-associated gastric ulcer 20 mg once daily for 4-8 weeks _
H. pylori eradication
(with 1000 mg Amoxicillin and 500 mg Clarithromycin)		 20 mg twice daily for 7 days 20 mg twice daily for 7 days
Zollinger-Ellison syndrome & idiopathic hypersecretion 40-80 mg twice daily _

Children 1-11 years:
  • Weight <20 kg: 10 mg once daily for 8 weeks
  • Weight ≥20 kg: 10 mg or 20 mg once daily for 8 weeks
Maintenance of healing of erosive esophagitis: 10 mg once daily.
Children below the age of 1 year: Maxora MUPS tablet is not approved for use in children younger than 1 year.